A mathematical model of T-cell effects in the humoral immune response

Numerical simulations of several mathematical models are used to compare possible roles of T-helper and T-suppressor cells in the humoral immune response. These simulations suggest that T-helper cells must help T-suppressor cells, and T-suppressor cells exert inhibition on all T-helper cell subpopulations. The models display the well-known phenomenon of memory, low zone and high zone tolerance.