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Constituents of flowers of Paeoniaceae plants,Paeonia suffruticosa and Paeonia lactiflora
Affiliation:1. State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, People''s Republic of China;2. Amore-Pacific R&D Center, 314-1, Bora-dong, Giheung-gu, Yongin-si, Gyeonggi-Do, 446-729, South Korea;1. College of Food and Bioengineering, Henan University of Science and Technology, Luoyang 471023, China;2. Henan Engineering Research Center of Food Material, Henan University of Science and Technology, Luoyang 471023, China;3. National Demonstration Center for Experimental Food Processing and Safety Education, Henan University of Science and Technology, Luoyang 471023, China
Abstract:A new monoterpene glycoside, floralalbiflorin I (1), and a new flavonol glycoside, lactifloraoside I (2), were isolated from the flowers of Paeonia suffruticosa and Paeonia lactiflora (Paeoniaceae) together with 28 known compounds. The chemical structures of the isolated compounds were elucidated on the basis of chemical and physicochemical evidence. Among the major constituents of P. suffruticosa and P. lactiflora flowers, 1,2,3,4,6-penta-O-galloyl-β-d-glucopyranoside (10) [inhibition: 42.4% at 1 μM] and flavonoids having the catechol moiety showed significant inhibitory effect on Cu2+-induced low-density lipoprotein (LDL) oxidation.
Keywords:Floralalbiflorin I  Lactifloraoside I  LDL oxidation  Paeoniaceae
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