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Bergenin glycosides from Rodgersia aesculifolia
Affiliation:1. Tianjin Key Laboratory for Modern Drug Delivery and High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, PR China;2. College of Life Sciences, Northwest A&F University, Shaanxi 712100, PR China;3. Tianjin Key Laboratory of TCM Chemistry and Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, PR China;1. Shaanxi Collaborative Innovation Center of Chinese Medicinal Resource Industrialization, Shaanxi Province Key Laboratory of New Drugs and Chinese Medicine Foundation Research, Shaanxi Rheumatism and Tumor Center of TCM Engineering Technology Research, School of Pharmacy, Shaanxi University of Chinese Medicine, Xianyang 712046, China;1. School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, China;2. School of Chinese Materia medica, Guangzhou University of Chinese Medicine, Guangzhou 510006, China;1. Shandong Analysis and Test Center, Shandong Academy of Sciences, Jinan 250014, P. R. China;2. Reyoung Pharmaceutical Co., Ltd, No. 44 Cultural West Road, Jinan 250012, P. R. China;1. Université Bordeaux, ISVV, Groupe d''Etude des Substances Végétales à Activité Biologique, EA 3675, 210 Chemin de Leysotte, F-33882 Villenave d''Ornon, France;2. Université Bordeaux, Institut Européen de Chimie et de Biologie Chimie et Biologie des Membranes et des Nanoobjets, 2, rue Robert Escarpit, 33607 Pessac, France;3. Université Bordeaux, ISVV, Unité de recherche Œnologie, EA 4577, INRA USC 1366, 210 Chemin de Leysotte, F-33882 Villenave d''Ornon, France
Abstract:Phytochemical investigation on Rodgersia aesculifolia afforded twenty-three compounds, including three bergenin glycosides, previously unknown in nature, together with twenty known compounds. Their structures were elucidated by the extensive use of 1D and 2D NMR experiments, along with IR and HRESIMS spectra. This is the first report of bergenin glycosides from nature.
Keywords:Saxifragaceae  Bergenin  Glycosides  Monoterpene disaccharide glycosides
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