Two new diketopiperazines and a new glucosyl sesterterpene from Alternaria alternata,an endophytic fungi from Ceratostigma griffithii |
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Affiliation: | 1. Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, PR China;2. Pharmacy School, Zunyi Medical College, Zunyi 563000, PR China;3. University of Chinese Academy of Sciences, Yuquan Road 19A, Beijing 100049, PR China;4. Syngenta Jealott’s Hill International Research Centre, Berkshire RG42 6EY, UK;1. Chinese Center for Chirality, Key Laboratory of Medicinal Chemistry and Molecular Diagnostics of Ministry of Education, Key Disciplines of Biotechnology Engineering of Hebei Province, Baoding 071002, China;2. The State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Kunming 650204, China;3. Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, Yunnan University, Kunming, China;1. School of Environment and Chemical Engineering, Nanchang Hangkong University, Nanchang 330063, PR China;2. Department of Chemistry and Biochemistry, The Ohio State University-Columbus, Columbus, OH 43210, United States;3. State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang 330047, PR China;1. Gansu Provincial Key Laboratory of Aridland Crop Science, College of Life Science and Technology, Gansu Agricultural University, Lanzhou 730070, China;2. Institute of Crop, Gansu Academy of Agricultural Sciences, Lanzhou 730070, China;1. The Key Laboratory of Biomedical Engineering, Ministry of Education, Zhejiang University, Hangzhou 310027, PR China;2. Shandong University of Traditional Chinese Medicine, Jinan 250355, PR China |
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Abstract: | Two diketopiperazine derivatives, altenarizines A (1) and B (2), and a new glucosyl sesterterpene, 24-α-d-glucosyl-(−)-terpestacin (3), together with two known phytotoxic sesterterpenes, (−)-terpestacin (4) and fusaproliferin (5), were isolated from the fermentation broth of an endophytic fungus Alternaria alternata, which was obtained from the fresh root of Ceratostigma griffithii. Structures of all the isolates were identified by spectroscopic data. |
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Keywords: | Diketopiperazine |
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