孕妇体内维生素D含量与新生儿湿疹的相关性

目的:研究孕妇维生素D(25(OH)D)含量与新生儿湿疹的关系,为改善孕期维生素D缺乏,预防婴儿湿疹提供临床依据。方法:选取2013年9月-2013年11月在我院生产的孕妇及所生的新生儿,调查研究对象的基本情况。采集孕妇的静脉血进行25(OH)D含量测定,并诊断新生儿湿疹的发生情况。结果:孕妇25(OH)D含量的中位数是15.17 ng/m L,新生儿湿疹的发病率是26.1%。孕妇不同含量25(OH)D水平与孕中晚期补充复合维生素、服用奶制品、摄入鱼蛋类次数、每天晒太阳时间等有关(P0.05);孕妇25(OH)D含量20 ng/m L会增加子女6个月内患湿疹的风险(OR=3.19,95%;CI:1.54,4.21)。结论:孕妇25(OH)D含量缺乏会增加新生儿湿疹的发病率。

Study on the Relationship between Pregnancy Vitamin DLevel and Infant Eczema

Objective:To analyze the relation between vitaminD (25 (OH) D) content in pregnancy and infant eczema, and toexplore the role of vitamin D level in pregnancy on the primary prevention of infant eczema.Methods:Pregnant women and infantsdelivered in our hospital fromSeptember 2013 to November 2013 were chosen. The basic information of the pregnant women and infantswas collercted and analyzed The venous blood was detected to determinate the 25 (OH) D concentration, and the eczema of the infantswas diagnosed.Results:The median of serum25(OH) D concentration in maternal was 15.17 ng/ml. 62 cases with eczema, the incidencewas 26.1%. Concentrations of 25 (OH) D levels in pregnant woman were correlated with the situation of supplement multivitamin, milkproducts, fish and eggs in the middle-late time of pregnancy, every day''s sunshine time (P<0.05). Pregnant women with serum 25(OH) Dconcentration<20 ng/ml will increase the risk of children eczema within six months.Conclusion:Pregnant women lacking 25(OH) D willincrease the risk of infant eczema at the age of 6 months.