1225例HIV/AIDS患者流行病学特征分析

目的:了解来陕西地区就诊的人类免疫缺陷病毒/艾滋病(Human immunodeficiency virus/Acquired immuno deficiency syndrome,HIV/AIDS)患者感染状况、流行特征。方法:收集来我院就诊的HIV/AIDS患者的基本信息,对其流行病学资料统计分析。结果:在调查的1225例HIV/AIDS患者中,男性占83.51%,平均年龄为(35.55±11.61)岁,50.98%为农民,小学及以下学历占33.55%,经血液途径感染250例,经性传播途径感染916例,其中同性性传播337例,经母婴垂直传播16例,就诊时CD4+T淋巴细胞计数平均值为(222.82±190.49)个/μL,56%的HIV/AIDS患者采用的抗病毒方案为齐多夫定(Zidovudine,AZT)/替诺福韦(Tenofovir Disoproxil Fumarate,TDF)+拉米夫定(Lamivudine,3TC)+依非韦伦(Efavirenz,EFV)方案。结论:陕西地区HIV/AIDS感染人数呈上升趋势,且年轻化加剧,同性性传播比例大幅增加。虽然治疗较为及时,应进一步在高危人群中积极宣传防艾知识与措施。

Epidemiological Characteristics of 1324 HIV/AIDS Patients

Objective:To understand the infection status and epidemiological characteristics of HIV/AIDS patients in Shaanxiprovince.Methods:The basic information of HIV/AIDS patients were collected in our clinic, and to analyze the epidemiologicalcharacteristics.Results:In the investigation of 1225 cases of HIV/AIDS infections, 83.51%were male, and the average age was (35.55±11.61) years old, 50.98%were farmers, and 33.55%of the patients'' education background were primary schooling or lower. 250 patientswere infected through blood-borne transmission, 916 patients were infected by sexual transmission, of whom 337 patients weretransmintted by homosexual behaviors, 16 patients were infected by vertical transmission. The average value of baseline CD4+T cellcount was (222.82 ± 190.49) cell/uL. 56% anti-retroviral therapeutic regimen was AZT/TDF+3TC+EFV.Conclusion:In Shaanxiprovince, the population of HIV/AIDS was on the increase and younger intensified. The proportion of homosexual transmission washigher. Although the treatment was in time, knowledge and methods of prevention should be disseminated in high-risk population.