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Inverted neurons in agyria |
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| Authors: | Cécile Bordarier O Robain Marie-Odile Rethoré O Dulac Caroline Dhellemes |
| Institution: | (1) Laboratoire de Neuropathologie, Hôpital Saint-Vincent de Paul, 74, avenue Denfert-Rochereau, F-75674 Paris Cedex 14, France;(2) Institut de Progenèse, 45, rue des Saints Pères, F-75270 Paris Cedex 06, France |
| Abstract: | Summary An anatomoclinical observation of agyria is reported. The karyotype revealed a partial deletion of the short arm of chromosome 17. The etiology of agyria is reviewed in the light of this chromosomal abnormality. In addition we describe the peculiar pattern of neurons in the cortex: Golgi stain demonstrated many inverted pyramidal cells in the superficial part of the cortical layer. The mechanism of this abnormality is discussed. |
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