Behavior of plasma cortisol in the course of testing with lysine-8-vasopressin and with lysine-8-vasopressin + resperine in normal subjects

Eight normal subjects were tested with LVP before and after treatment with Reserpine. The results show that Reserpine inhibits the cortisolemic response to the LVP test. This effect can most likely be attributed to the depletion of catecholamines induced by these drugs on the CNS and, in particular, in the Hypothalamus.