| 巴戟天寡糖提纯工艺及药理作用研究进展 |
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| 引用本文： | 李鑫洁,李玲玲,鲁艺.巴戟天寡糖提纯工艺及药理作用研究进展[J].天然产物研究与开发,2019(2):345-353. |
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| 作者姓名： | 李鑫洁 李玲玲 鲁艺 |
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| 作者单位： | 北京中医药大学中医学院 |
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| 基金项目： | 教育部新世纪优秀人才项目(NCET-13-0695);国家自然科学基金(81102623);北京中医药大学科研发展基金(2010072120015);北京中医药新奥奖励基金(1000062720063/007/001);北京市自然科学基金(18G40092) |
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| 摘 要： | 现代研究巴戟天寡糖具有抗抑郁、神经保护等功效,且毒副作用较小,然而其在提纯与检测技术上存在一定难度,是现代研究领域的困扰之一。本文通过检索中国知网、百度学术、万方、维普、Pub Med、Science等数据库,归纳整理近年来国内外与巴戟天寡糖相关文献,论述其提纯、成分检测方法以及临床药理作用,为深入探讨巴戟天发挥药效机制、进一步开发巴戟天新药提供科学依据,尽可能提高巴戟天的利用价值。
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| 关 键 词： | 巴戟天 寡糖 提纯检测 药理作用 研究进展 |
The research of Morinda officinalis How's oligosaccharide extraction,purification and pharmacological effects |
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| LI Xin-jie,LI Ling-ling,LU Yi.The research of Morinda officinalis How's oligosaccharide extraction,purification and pharmacological effects[J].Natural Product Research and Development,2019(2):345-353. |
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| Authors: | LI Xin-jie LI Ling-ling LU Yi |
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| Institution: | (School of Traditional Chinese Medicine,Beijing University of Chinese Medicine,Beijing 100029,China) |
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| Abstract: | Morinda officinalis How’s Oligosaccharide had the functions of anti-depressant,neuroprotection and so on,but it had some difficulty in purification and detection technology,which was one of the puzzles in modern research field.The author summarized the relevant literatures with oligosaccharides at home and abroad,and discussed their separation,detection methods and clinical pharmacology in recent years,by searching China Knowledge Network,Baidu Academic,Wanfang,Weipu,pubMed,Science and other databases.In order to further explore the mechanism of Morinda officinalis and further develop Morinda officinalis,this study provided a scientific basis to maximize the use of Morinda officinalis value. |
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| Keywords: | Morinda officinalis How oligosaccharide purification pharmacological effects research progress |
| 本文献已被 CNKI 维普 等数据库收录！ |
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