| 短角湿生冷水花化学成分的研究 |
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| 引用本文： | 周鹏军,杨国勋,张梦甜,屠娇,温宝莹,丁杰,胡金锋.短角湿生冷水花化学成分的研究[J].天然产物研究与开发,2019(5):826-831. |
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| 作者姓名： | 周鹏军 杨国勋 张梦甜 屠娇 温宝莹 丁杰 胡金锋 |
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| 作者单位： | 四川轻化工大学化学工程学院;复旦大学药学院天然药物化学教研室 |
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| 基金项目： | 国家自然科学基金(81773599);上海科技基金项目(12401901001) |
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| 摘 要： | 为研究短角湿生冷水花(Pilea aquarum subsp.brevicornuta)化学成分。实验采用色谱法从中分离得到7个化合物,包括5个五环三萜、一个甾醇和一个木脂素。利用波谱学方法鉴定了它们的结构,分别鉴定为pilearbornol(1)、rubiarbonone D(2)、camarolide(3)、表齐墩果酸(4)、齐墩果酮酸(5)、5,8-epidioxy-(3β,5α,8α,22E)-ergosta-6,9(11),22-trien-3-ol(6)和桉脂素(7)。其中,化合物1和2属于乔木萜烷型(arborane)三萜,化合物1为新化合物,化合物2的绝对构型首次通过X-射线单晶衍射得到了确定。所有化合物均为首次从该植物中分离得到,这也是首次从荨麻科植物中分离得到乔木萜烷型三萜化合物。
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| 关 键 词： | 短角湿生冷水花 乔木萜烷 三萜 绝对构型 |
Chemical constituents from Pilea aquarum subsp.brevicornuta |
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| ZHOU Peng-jun,YANG Guo-xun,ZHANG Meng-tian,TU Jiao,WEN Bao-ying,DING Jie,HU Jin-feng.Chemical constituents from Pilea aquarum subsp.brevicornuta[J].Natural Product Research and Development,2019(5):826-831. |
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| Authors: | ZHOU Peng-jun YANG Guo-xun ZHANG Meng-tian TU Jiao WEN Bao-ying DING Jie HU Jin-feng |
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| Institution: | (School of Chemical Engineering,Sichuan University of Science & Engineering,Zigong 643000,China;Department of Natural Products Chemistry,School of Pharmacy,Fudan University,Shanghai 201203,China) |
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| Abstract: | The study was focus on the chemical constituents of Pilea aquarum subsp. brevicornuta and seven compounds were obtained. Their structures were identified as pilearbornol ( 1),rubiarbonone D ( 2),camarolide ( 3),epi-oleanolic acid ( 4), oleanonic acid ( 5),5,8-epidioxy-( 3β,5α,8α,22E)-ergosta-6,9( 11),22-trien-3-ol ( 6) and eudesmin ( 7),respectively,by spectroscopic methods. Among them,compounds 1 and 2 belong to arborane-type triterpenoids and compound 1 is new. In ad- dition,the absolute configuration of compound 2 was determined by X-ray crystal diffraction. All isolates were discovered from this plant for the first time and this is the first time to report arborane triterpenoids from Urticaceae family. |
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| Keywords: | Pilea aquarum subsp brevicornuta arborane triterpenoids absolute configuration |
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