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麻楝果实化学成分及其抗烟草青枯病菌活性的研究
引用本文:刘慧,刘寿柏,王昊,陈惠琴,王佩,梅文莉,杨克军,戴好富. 麻楝果实化学成分及其抗烟草青枯病菌活性的研究[J]. 天然产物研究与开发, 2019, 0(6): 1023-1029,974
作者姓名:刘慧  刘寿柏  王昊  陈惠琴  王佩  梅文莉  杨克军  戴好富
作者单位:黑龙江八一农垦大学农学院;中国热带农业科学院热带生物技术研究所农业部热带作物生物学与遗传资源利用重点实验室;海南大学热带农林学院
基金项目:海南省自然科学基金创新研究团队项目(2017CXTD0 20);中国热带农业科学院基本科研业务费专项资金(17CXTD-15,1630052016008);现代农业产业技术体系建设专项资金项目(CARS-21)
摘    要:为研究麻楝(Chukrasia tabularis)的化学成分,采用色谱法从麻楝果实乙醇提取物中分离得到15个化合物,利用波谱学方法鉴定其结构分别为:没食子酸甲酯(1)、没食子酸乙酯(2)、没食子酸(3)、ozoroalide(4)、stigmast-4-en-6β-ol-3-one(5)、黄柏呈(6)、chukranin A(7)、chisopanin M(8)、21α,24α-methylmelianodiol(9)、toonaciliatin K(10)、21α,25-dimethylmelianodiol(11)、odoratone(12)、bourjotinolone A(13)、hispidone(14)和phragmalin di-isobutyrate(15)。化合物4~14为首次从麻楝属植物中分离得到。采用滤纸片琼脂扩散法对单体化合物进行抗烟草青枯病菌(Ralstonia solanacearum)的活性研究,结果表明化合物1、2和3具有中等拮抗活性。

关 键 词:麻楝  果实  化学成分  烟草青枯病菌

Chemical constituents from the fruits of Chukrasia tabularis and their anti-bacterial activity against Ralstonia solanacearum
Affiliation:(College of Agriculture,Heilongjiang Bayi AgriculturalUniversity,Daqing 163000 ,China;Key Laboratory of Biology and Genetic Resources of TropicalCrops,Ministry of Agriculture,Institute ofTropical Bioscience and Biotechnology,Chinese Academy ofTropical Agricultural Sciences,Haikou 571101 ,China;Institute of Tropical Agriculture and Forestry,HainanUniversity,Haikou 570228 ,China)
Abstract:In order to study the chemical constituents of Chukrasia tabularis,fifteen compounds were isolated from the ethanol extract of the fruits of Chukrasia tabularis by chromatographic methods.Their structures were identified as methyl gallate(1),ethyl gallate(2),gallic acid(3),ozoroalide(4),stigmast-4-en-6β-ol-3-one(5),phellochin(6),chukranin A(7),chisopanin M(8),21α,24α-methylmelianodiol(9),toonaciliatin K(10),21α,25-dimethylmelianodiol(11),odoratone(12),bourjotinolone A(13) hispidone(14),and phragmalin di-isobutyrate(15) by spectroscopic methods.Compounds 4~14 were isolated from the genus Chukrasia for the first time.All the compounds were assayed of the anti-bacterial activity against Ralstonia solanacearum by paper disco diffusion method.Among them,compounds 1,2,and 3 exhibited moderate inhibitory activity.
Keywords:Chukrasia tabularis  fruits  chemical constituents  Ralstonia solanacearum
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