Nonsense-missense suppression in yeast |
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Authors: | B V Simarov L N Mironova and S G Inge-Vechtomov |
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Institution: | (1) Department of Genetics, Leningrad State University, Leningrad, USSR |
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Abstract: | Summary A dominant suppressor has been discovered which suppresses polarity type mutations, noncomplementing ones and those belonging to short nonpolar complementation groups at the ad
2 locus of S. cerevisiae. The suppressor translates two types of nonsense previously established at ad
2. These data together with theoretical consideration of relationships between nonsense-translating anticodons and different codons make it possible to suggest a mechanism for the observed suppression. According to this mechanism two nonsense types of ad
2 are identified as amber and ochre codons. |
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