Comparison of Vanadium-Rich Activity of Three Species Fungi of Basidiomycetes |
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Authors: | Chunchao Han Bo Cui Jingran Qu |
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Affiliation: | (1) School of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China;(2) College of Food and Bioengineering, Shandong Institute of Light Industry, Jinan, 250353, People’s Republic of China |
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Abstract: | A comparison of vanadium-rich activity of three species fungi of Basidiomycetes, Ganoderma lucidum, Coprinus comatus, and Grifola frondosa, was studied. By fermentation and atomic absorption spectroscopy analysis, the biomass of G. lucidum and G. frondosa declined rapidly when the concentration of vanadium exceeded 0.3% but the biomass of C. comatus did not decline rapidly until the concentration of vanadium exceeded 0.4% and the content of vanadium accumulated in the mycelia was 3529.3 μg/g. After the mice were administered (intragastrically) with vanadium-rich C. comatus, the blood glucose of alloxan-induced hyperglycemic mice was decreased (p < 0.05) and the body weight of the alloxan-induced hyperglycemic mice was increased gradually. Thus, we selected C. comatus to absorb vanadium and chose 0.4% as the optimal concentration of vanadium for the pharmacological works. |
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Keywords: | Vanadium Ganoderma lucidum Coprinus comatus Grifola frondosa Basidiomycetes |
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