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Formation of immune proteasomes and development of immune system in ontogenesis of mammals |
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| Authors: | N P Sharova T M Astakhova L A Bondareva S B Dmitrieva S D Stolyarov |
| Institution: | (1) Kol’tsov Institute of Developmental Biology, Russian Academy of Sciences, u. Vavilova 26, Moscow, 119334, Russia;(2) Institute of Biology, Karelian Research Center of the Russian Academy of Sciences, Pushkinskaya ul., 11, Petrozavodsk, 185610, Russia |
| Abstract: | Current concepts of the structure of immune proteasomes and their role in immune response have been considered. The main attention has been paid to the formation of immune proteasomes in secondary lymphoid and nonlymphoid organs during ontogenesis of mammals. The causes of ineffective formation of immune system in early postnatal development have been discussed. |
| Keywords: | immune proteasomes T-cellular immunity development of immune system |
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