| 二十碳五烯酸和二十二碳六烯酸的生物合成途径研究进展 |
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| 引用本文： | 孙晓艳,林艳丽,熊福银,刘蓥灿,李力,陈红星. 二十碳五烯酸和二十二碳六烯酸的生物合成途径研究进展[J]. 生物技术通讯, 2012, 0(5): 755-758 |
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| 作者姓名： | 孙晓艳 林艳丽 熊福银 刘蓥灿 李力 陈红星 |
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| 作者单位： | 1. 陕西师范大学生命科学学院，陕西西安71006
2. 军事医学科学院生物工程研究所，北京100071 |
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| 摘 要： | 以二十碳五烯酸(EPA)和二十二碳六烯酸(DHA)为代表的长链多不饱和脂肪酸,对人体心血管系统、神经系统、抗炎免疫系统等有着理想的功效,因而倍受研究者关注。我们从结构、生物来源和合成、生理功能及生物工程途径的研究现状等方面阐述了EPA和DHA的相关信息,并对其生成途径中涉及的酶进行了简要概述。
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| 关 键 词： | 长链多不饱和脂肪酸 二十碳五烯酸 二十二碳六烯酸 Δ6去饱和酶 Elovl2延长酶 |
Progresses on Biosynthesis of Eicosapentaenoic Acid and Docosa hexaenoic Acid |
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| SUN Xiao-Yan,LIN Yan-Li,XIONG Fu-Yin,LIU Ying-Can,LI Li,CHEN Hong-Xing. Progresses on Biosynthesis of Eicosapentaenoic Acid and Docosa hexaenoic Acid[J]. Letters in Biotechnology, 2012, 0(5): 755-758 |
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| Authors: | SUN Xiao-Yan LIN Yan-Li XIONG Fu-Yin LIU Ying-Can LI Li CHEN Hong-Xing |
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| Affiliation: | 1.College of Life Science,Shaanxi Normal University,Xi’an 710062;2.Beijing Institute of Biotechnology,Beijing 100071;China |
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| Abstract: | Eicosapentaenoic acid(EPA) and docosahexaenoic acid(DHA) as the representative of long-chain poly unsaturated fatty acids,researchers has paied much attention on them,because it has ideal treatment effect about cardiovascular system,nervous system,immune system of human.In this article,we described information about EPA and DHA from aspects of the structure,biological origin and biosynthesis,physical function,progresses on bio-engineering approach,and related enzymes in biosynthesis were introduced briefly. |
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| Keywords: | long-chain polyunsaturated fatty acids eicosapentaenoic acid docosahexaenoic acid Δ6 desaturase Elovl2 elongase |
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