Common cellular events occur during wound healing and organ regeneration in the sea cucumber <Emphasis Type="Italic">Holothuria glaberrima</Emphasis> |
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Authors: | José E San Miguel-Ruiz José E García-Arrarás |
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Institution: | (1) Department of Biology, University of Puerto Rico, Rio Piedras, Puerto Rico |
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Abstract: | Background All animals possess some type of tissue repair mechanism. In some species, the capacity to repair tissues is limited to the
healing of wounds. Other species, such as echinoderms, posses a striking repair capability that can include the replacement
of entire organs. It has been reported that some mechanisms, namely extracellular matrix remodeling, appear to occur in most
repair processes. However, it remains unclear to what extent the process of organ regeneration, particularly in animals where
loss and regeneration of complex structures is a programmed natural event, is similar to wound healing. We have now used the
sea cucumber Holothuria glaberrima to address this question. |
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Keywords: | |
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