X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family |
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| Authors: | Rajiv Tyagi Stephen K Burley Subramanyam Swaminathan |
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| Affiliation: | (1) Biology Department, Brookhaven National Laboratory, Upton, New York, 11973, USA;(2) SGX Pharmaceuticals, Inc., San Diego, California 92121, USA |
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| Abstract: | Background Pfam is a comprehensive collection of protein domains and families, with a range of well-established information including genome annotation. Pfam has two large series of functionally uncharacterized families, known as Domains of Unknown Function (DUFs) and Uncharacterized Protein Families (UPFs). |
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