Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D |
| |
| Authors: | Aleksey Porollo,Jaroslaw Meller |
| |
| Affiliation: | (1) Department of Environmental Health, University of Cincinnati, Cincinnati, OH 45267, USA;(2) Department of Biomedical Engineering, University of Cincinnati, Cincinnati, OH 45267, USA;(3) Division of Biomedical Informatics, Children's Hospital Research Foundation, Cincinnati, OH 45229, USA;(4) Department of Informatics, Nicholas Copernicus University, 87-100 Torun, Poland |
| |
| Abstract: | Background Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing significantly towards the understanding of molecular systems and processes. For example, three dimensional (3D) models help in exploring protein active sites and functional hot spots that can be targeted in drug design. Automated annotation and visualization pipelines can also reveal other functionally important attributes of macromolecules. These goals are dependent on the availability of advanced tools that integrate better the existing databases, annotation servers and other resources with state-of-the-art rendering programs. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
