Prediction of protein-protein binding site by using core interface residue and support vector machine |
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| Authors: | Nan Li Zhonghua Sun Fan Jiang |
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| Affiliation: | (1) Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing, 100080, PR, China;(2) Graduate School of the Chinese Academy of Sciences, Beijing, PR, China |
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| Abstract: | Background The prediction of protein-protein binding site can provide structural annotation to the protein interaction data from proteomics studies. This is very important for the biological application of the protein interaction data that is increasing rapidly. Moreover, methods for predicting protein interaction sites can also provide crucial information for improving the speed and accuracy of protein docking methods. |
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