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K2D2: Estimation of protein secondary structure from circular dichroism spectra |
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| Authors: | Carolina Perez-Iratxeta Miguel A Andrade-Navarro |
| Affiliation: | 1.Ontario Genomics Innovation Centre,Ottawa Health Research Institute,Ottawa,Canada;2.Department of Cellular and Molecular Medicine, Faculty of Medicine,University of Ottawa,Canada;3.Computational Biology and Data Mining Group,Max Delbrück Centre for Molecular Medicine,Berlin,Germany |
| Abstract: | BackgroundCircular dichroism spectroscopy is a widely used technique to analyze the secondary structure of proteins in solution. Predictive methods use the circular dichroism spectra from proteins of known tertiary structure to assess the secondary structure contents of a protein with unknown structure given its circular dichroism spectrum. |
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