Prevention by polyhydroxysteroids and saponins of Asterina pectinifera of the desquamation of stratum corneum cells |
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| Authors: | Ukai Kazuyo Iwanaga Atsufumi Nagai Hiroshi Namikoshi Michio |
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| Institution: | Department of Ocean Sciences, Tokyo University of Fisheries, Japan. |
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| Abstract: | Two polyhydroxysteroids and three steroidal saponins (pectiniosides A, B and C) were isolated as bioactive substances from Asterina pectinifera. These compounds inhibited the release of guinea-pig skin stratum corneum cells by 48-67% (control, 0%) at 2 mg/ml. It is suggested that the bioactivity of these compounds is connected with the remedial and preventive effects of an aqueous extract of A. pectinifera on rough human skin. |
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