1H, 13C and 15N resonance assignments of RNA pyrophosphohydrolase RppH from Escherichia coli |
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| Authors: | Yunchen Bi Hongwei Li Shoujin Fan Bin Xia Changwen Jin |
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| Institution: | (1) Beijing Nuclear Magnetic Resonance Center, Peking University, 100871 Beijing, China;(2) College of Life Sciences, Shandong Normal University, 250014 Jinan, China;(3) College of Chemistry and Molecular Engineering, Peking University, 100871 Beijing, China;(4) College of Life Sciences, Peking University, 100871 Beijing, China |
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| Abstract: | The mRNA degradation is an important regulatory mechanism which controls gene expression by limiting the number of translation
times. Previous studies demonstrated that this process is essential for organisms. Escherichia coli RNA pyrophosphohydrolase (RppH) is an enzyme that triggers mRNA degradation by removing the 5′ pyrophosphate, which is a
rate-determining step. In order to understand the molecular mechanism of the biological function, the structural information
of RppH is required. Herein, we report the resonance assignments of 1H, 15N, 13C atoms of the E. coli RppH. |
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| Keywords: | RppH mRNA degradation Assignments NMR |
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