Three new koninginins from Trichoderma neokongii 8722 |
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| Affiliation: | 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, China;2. University of Chinese Academy of Sciences, Beijing 100049, China;1. Foodborne Toxin Detection and Prevention, Western Regional Research Center, Agricultural Research Service, United States Department of Agriculture, 800 Buchanan Street, Albany, CA 94710, United States;2. Poisonous Plant Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 1150 East 1400 North, Logan, UT 84341, United States;3. Paramount Farming Company, 33141 E. Lerdo Highway, Bakersfield, CA 93308, United States;1. Department of Chemistry, University of Nairobi, P.O. Box 30197-00100, Nairobi, Kenya;2. Global Emerging Infections Surveillance (GEIS) Program, United States Army Medical Research Unit-Kenya (USAMRU-K), Kenya Medical Research Institute (KEMRI) – Walter Reed Project, P.O. Box 54 - 40100, Kisumu, Kenya;3. Institut für Chemie, Universität Potsdam, P.O. Box 60 15 53, D-14415 Potsdam, Germany;1. Chulabhorn Research Institute and Chulabhorn Graduate Institute, Kamphaeng Phet 6, Talat Bang Khen, Lak Si, Bangkok 10210, Thailand;2. Center of Excellence on Environment Health and Toxicology, CHE, Ministry of Education, Thailand;3. Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand;1. School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing 210009, PR China;2. Department of Phytochemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, PR China;3. King Saud University, Riyadh 11451, Saudi Arabia;4. School of Pharmacy, Shanghai Jiao Tong University, Shanghai 200240, PR China |
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| Abstract: | Three new fungal metabolites, named koninginins I (1), J (2) and K (3) together with four known koninginins A (4), B (5), D (6) and E (7), were isolated from solid fermentation products of Trichoderma neokongii 8722. Three new structures were elucidated by extensive spectroscopic methods, including 1D NMR and 2D NMR, and HR-ESI–MS experiments. |
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| Keywords: | Chemical constituents Structure identification Koninginin |
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