One new flavonoid xyloside and one new natural triterpene rhamnoside from the leaves of Syzygium grande |
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Institution: | 1. College of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk 712-749, Republic of Korea;2. Department of Pharmacognosy and Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, MS 38677, USA;3. College of Pharmacy, CMRI, Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu 702-701 and 700-422, Republic of Korea;4. BK21 Plus KNU Biomedical Convergence Program, Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Daegu 702-701 and 700-422, Republic of Korea;5. College of Pharmacy, Chungnam National University, Daejeon 305-764, Republic of Korea;6. National Center for Natural Products Research, The University of Mississippi, University, MS 38677, USA |
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Abstract: | One new flavonoid glycoside, myricetin 4′-methyl ether 3-O-β-d-xylopyranoside (1) and one new natural triterpene glycoside, grandoside (2) were isolated from a MeOH extract of the leaves of Syzygium grande, together with thirteen known compounds (3–15). The structures of the new compounds were determined through a combination of spectroscopic and chemical analyses. All of the isolated compounds were evaluated for their antifungal, antibacterial, anti-leishmania, DPPH radical-scavenging and cytotoxic activities by means of MTT assay. |
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Keywords: | Myrtaceae Grandoside |
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