Identification and biological activity of secondary metabolites from Dryobalanops beccarii |
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| Institution: | 1. Centre for Experimental Medicine, Queen’s University of Belfast, Belfast, N. Ireland;2. University of Sydney, NHMRC Clinical Trials Centre, Camperdown, Sydney, NSW, Australia;3. Section of Endocrinology and Diabetes, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA;4. College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA;5. Hines VA Cooperative Studies Program (CSP) Coordinating Center, Edward Hines Jr. VA Hospital, Hines, IL, USA;6. Ross Eye Institute, Department of Ophthalmology, State University of New York at Buffalo, Buffalo, NY, USA;7. Division of Endocrinology, Medical University of South Carolina, Charleston, SC, USA;8. Department of Physiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA |
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| Abstract: | A new trimeric oligostilbene, malaysianol D (1) and galloylglucoside, malaysin A (2), together with twelve known compounds (3–14) have been isolated from the methanol extract of the stem bark of Dryobalanops beccarii by combination of vacuum and radial chromatography techniques. Their structures were established on the basis of their spectroscopic evidence and comparison with the published data. The cytotoxic activity of isolated compounds was tested against A549 and MCF-7 cancer cell lines. |
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| Keywords: | Dipterocarpaceae Oligostilbenoid Malaysianol D Malaysin A and cytotoxic |
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