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Three new C19-diterpenoid alkaloids from Delphinium tianshanicum W. T. Wang
Affiliation:1. Key Laboratory of Plants Resources and Chemistry of Arid Zone, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing South Road 40-1, Urumqi 830011, Xinjiang, PR China;2. S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashken, Uzbekistan;3. State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Urumqi 830011, PR China;4. University of Chinese Academy of Sciences, Beijing 100039, PR China;1. State Key Laboratory of Organic–Inorganic Composites, Beijing University of Chemical Technology, 100029 Beijing, PR China;2. Institute of Chemical Sciences, Gomal University, Dera Ismail Khan, KP, Pakistan;1. Department of Chemistry, University of Nairobi, P.O. Box 30197-00100, Nairobi, Kenya;2. Institut für Chemie, Universität Potsdam, Karl-Liebknecht-Str. 24-25, D-14476 Potsdam, Germany;3. Global Emerging Infections Surveillance (GEIS) Program, United States Army Medical Research Unit-Kenya (USAMRU-K), Kenya Medical Research Institute (KEMRI) – Walter Reed Project, Kisumu and Nairobi, Kenya;1. Faculty of Pharmacy, Umm Al-Qura University, Makka, Saudi Arabia;2. Faculty of Pharmacy (Girls), Al-Azhar University, Nasr-City, Cairo, Egypt;3. Faculty of Pharmacy, Egyptian-Russian University, Cairo, Egypt;4. National Organization for Drug Control and Research, Dokki, P.O. 29, Cairo, Egypt;1. Department of Organic Chemistry, Faculty of Science, The University of Yaoundé I, P.O. Box 812, Yaounde, Cameroon;2. Institute of Medical Research and Medicinal Plant Studies, Ministry of Scientific Research and Innovation, P.O. Box 6163, Yaoundé, Cameroon;3. Department of Chemistry, University of Botswana, Private Bag 00704, Gaborone, Botswana;4. Department of Chemistry, Joseph Black Building, University of Glasgow, Glasgow G12 8QQ, Scotland;1. Key Laboratory of Chemistry in Ethnic Medicinal Resources, State Ethnic Affairs Commission & Ministry of Education, Yunnan Minzu University, Kunming 650031, PR China;2. Yunnan Academy of Tobacco Science, China Tobacco Yunnan Industrial Co., Ltd., Kunming 650106, PR China
Abstract:Three new C19-diterpenoid alkaloids, tianshanisine (1), tianshanine (2) and tianshanidine (3), together with six known C19-diterpenoid alkaloids (4–9) were isolated from the whole herb of Delphinium tianshanicum W. T. Wang. Their structures were established on the basis of spectroscopic analyses, including HR-ESI-MS and 1D and 2D NMR.
Keywords:Diterpenoid alkaloids  Tianshanisine  Tianshanine  Tianshanidine
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