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Molecular docking analysis of aspirin analogues with β-catenin
Authors:Jayaraman Selvaraj  Hussain Sardar  Veeraraghavan Vishnupriya  Janardhana Papayya Balakrishna  Surapaneni Krishna Mohan  Rajamanickam Pon Nivedha  Periyasamy Vijayalakshmi  Rajagopal Ponnulakshmi
Abstract:Canonical Wnt signaling pathway plays a crucial role in cancer cell proliferation, which links by the growth of β-catenin in cell due to inactivation of glycogen synthetase kinase-3. Therefore, it is of interest to design novel candidates to bind with β-catenin. Hence, we document the molecular docking analysis data of aspirin analogues with β-catenin for further consideration.
Keywords:Colon cancer   Wnt signaling   molecular docking   ADME
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