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Inducible and constitutive nucleoside-binding sites in Escherichia coli: differential inhibition by nucleoside analogues
Authors:Doskocil J  Holý A
Affiliation:Institute of Organic Chemistry and Biochemistry, Czechoslovak Academy of Sciences, 166 10 Praha - Dejvice, Flemingovo 2, Czechoslovakia
Abstract:Constitutive and inducible nucleoside-binding sites on the surface of the cells of E. coli B have different patterns of inhibition by nucleoside analogues. 1(β-D-Ribofuranosyl)-4-aminopyrimidine-6-one and isoguanosine preferentially inhibit the inducible binding sites while showdomycin and N4-dimethylcytidine interfere more strongly with the constitutive function.
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