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Differential selection on gene translation efficiency between the filamentous fungus Ashbya gossypii and yeasts
Authors:Huifeng Jiang  Yue Zhang  Jun Sun  Wen Wang  Zhenglong Gu
Affiliation:(1) Division of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA;(2) CAS-Max Planck Junior Research Group, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences (CAS), Kunming, Yunnan, 650223, PR China;(3) Graduate School of Chinese Academy Sciences, Beijing, 100039, PR China;(4) State Key Laboratory of Cellular and Molecular Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, Yunnan Province, PR China
Abstract:

Background  

The filamentous fungus Ashbya gossypii grows into a multicellular mycelium that is distinct from the unicellular morphology of its closely related yeast species. It has been proposed that genes important for cell cycle regulation play central roles for such phenotypic differences. Because A. gossypii shares an almost identical set of cell cycle genes with the typical yeast Saccharomyces cerevisiae, the differences might occur at the level of orthologous gene regulation. Codon usage patterns were compared to identify orthologous genes with different gene regulation between A. gossypii and nine closely related yeast species.
Keywords:
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