The crystal structure of the putative peptide-binding fragment from the human Hsp40 protein Hdj1 |
| |
| Authors: | Junbin Hu Yunkun Wu Jingzhi Li Xinguo Qian Zhengqing Fu Bingdong Sha |
| |
| Affiliation: | (1) Department of Cell Biology, University of Alabama at Birmingham, Birmingham, AL 35294, USA;(2) SER-CAT, APS, Argonne National Laboratory, 9700 S. Cass Ave., Argonne, IL 60439, USA |
| |
| Abstract: | Background The mechanism by which Hsp40 and other molecular chaperones recognize and interact with non-native polypeptides is a fundamental question. How Hsp40 co-operates with Hsp70 to facilitate protein folding is not well understood. To investigate the mechanisms, we determined the crystal structure of the putative peptide-binding fragment of Hdj1, a human member of the type II Hsp40 family. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
|
