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SODa: An Mn/Fe superoxide dismutase prediction and design server |
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| Authors: | Jean Marc Kwasigroch René Wintjens Dimitri Gilis Marianne Rooman |
| Institution: | (1) Unit de Bioinformatique gnomique et structurale, Universit Libre de Bruxelles, CP 165/61, avenue Roosevelt 50, B-1050 Brussels, Belgium;(2) Service de Chimie gnrale, Universit Libre de Bruxelles, CP 206/04, boulevard du Triomphe, B-1050 Brussels, Belgium |
| Abstract: | BackgroundSuperoxide dismutases (SODs) are ubiquitous metalloenzymes that play an important role in the defense of aerobic organisms against oxidative stress, by converting reactive oxygen species into nontoxic molecules. We focus here on the SOD family that uses Fe or Mn as cofactor. |
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