SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

SNPHunter: a bioinformatic software for single nucleotide polymorphism data acquisition and management

Authors:	Lin?Wang,Simin?Liu,Tianhua?Niu author-information" > author-information__contact u-icon-before" > mailto:tniu@hsph.harvard.edu" title=" tniu@hsph.harvard.edu" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Xin?Xu

Affiliation:	(1) Program for Population Genetics, Harvard School of Public Health, Boston, MA 02115, USA;(2) Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA;(3) Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02215, USA

Abstract:	Background Single nucleotide polymorphisms (SNPs) provide an important tool in pinpointing susceptibility genes for complex diseases and in unveiling human molecular evolution. Selection and retrieval of an optimal SNP set from publicly available databases have emerged as the foremost bottlenecks in designing large-scale linkage disequilibrium studies, particularly in case-control settings.

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