Cytotoxic hydroazulene diterpenes from the brown alga Cystoseira myrica |
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Authors: | Ayyad Seif-Eldin N Abdel-Halim Osama B Shier W Thomas Hoye Thomas R |
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Affiliation: | Department of Chemistry, Faculty of Science, Mansoura University, New Damietta, Egypt. snayyad@mans.edu.eg |
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Abstract: | Cytotoxicity-guided fractionation of the alcohol extract of the brown alga, Cystoseira myrica, afforded four new cytotoxic hydroazulene diterpenes, dictyone acetate (2), dictyol F monoacetate (4), isodictytriol monoacetate (6), and cystoseirol monoacetate (8), together with two known cytotoxic hydroazulene diterpenes, pachydictyol A (1) and dictyone (3). The constitution of each isolated compound has been determined on the basis of spectroscopic and chemical evidence. |
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