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Cytotoxic hydroazulene diterpenes from the brown alga Cystoseira myrica
Authors:Ayyad Seif-Eldin N  Abdel-Halim Osama B  Shier W Thomas  Hoye Thomas R
Affiliation:Department of Chemistry, Faculty of Science, Mansoura University, New Damietta, Egypt. snayyad@mans.edu.eg
Abstract:Cytotoxicity-guided fractionation of the alcohol extract of the brown alga, Cystoseira myrica, afforded four new cytotoxic hydroazulene diterpenes, dictyone acetate (2), dictyol F monoacetate (4), isodictytriol monoacetate (6), and cystoseirol monoacetate (8), together with two known cytotoxic hydroazulene diterpenes, pachydictyol A (1) and dictyone (3). The constitution of each isolated compound has been determined on the basis of spectroscopic and chemical evidence.
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