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Enhancement of farnesyl diphosphate pool as direct precursor of sesquiterpenes through metabolic engineering of the mevalonate pathway in Saccharomyces cerevisiae
Authors:Mohammad A Asadollahi  Jérôme Maury  Michel Schalk  Anthony Clark  Jens Nielsen
Institution:1. Department of Systems Biology, Center for Microbial Biotechnology (CMB), Building 223, Technical University of Denmark (DTU), DK‐2800 Kgs. Lyngby, Denmark;2. telephone: 46‐31‐772‐38‐04;3. fax: 46‐31‐772‐38‐01;4. Faculty of Advanced Sciences and Technologies, Biotechnology Group, University of Isfahan, Isfahan, Iran;5. Firmenich SA, Corporate R&D Division, Geneva, Switzerland;6. Firmenich Inc., Corporate R&D Division, Princeton, New Jersey
Abstract:
Keywords:metabolic engineering  Saccharomyces cerevisiae  sesquiterpene  mevalonate pathway  farnesyl diphosphate  squalene
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