Parallel kinetic resolution of D‐labelled 2‐aryl‐propionic and butanoic acids using quasi‐enantiomeric combinations of oxazolidin‐2‐ones |
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| Authors: | Elliot Coulbeck Marco Dingjan Jason Eames |
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| Affiliation: | 1. Department of Chemistry, University of Hull, Hull HU6 7RX, United Kingdom;2. Department of Chemistry, Queen Mary, University of London, London E1 4NS, United Kingdom |
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| Abstract: | The parallel kinetic resolution of racemic 2‐aryl‐2‐deuterio‐propionic and butanoic acids using an equimolar combination of quasi‐enantiomeric oxazolidin‐2‐ones is discussed. The levels of diastereoselectivity were high leading to enantiomerically pure D ‐labeled products in good yield. Chirality, 2010. © 2009 Wiley‐Liss, Inc. |
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| Keywords: | parallel kinetic resolution kinetic resolution quasi‐enantiomers 2‐phenylpropionic acid resolution oxazolidin‐2‐ones |
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