Parallel kinetic resolution of D‐labelled 2‐aryl‐propionic and butanoic acids using quasi‐enantiomeric combinations of oxazolidin‐2‐ones |
| |
| Authors: | Elliot Coulbeck Marco Dingjan Jason Eames |
| |
| Institution: | 1. Department of Chemistry, University of Hull, Hull HU6 7RX, United Kingdom;2. Department of Chemistry, Queen Mary, University of London, London E1 4NS, United Kingdom |
| |
| Abstract: | The parallel kinetic resolution of racemic 2‐aryl‐2‐deuterio‐propionic and butanoic acids using an equimolar combination of quasi‐enantiomeric oxazolidin‐2‐ones is discussed. The levels of diastereoselectivity were high leading to enantiomerically pure D ‐labeled products in good yield. Chirality, 2010. © 2009 Wiley‐Liss, Inc. |
| |
| Keywords: | parallel kinetic resolution kinetic resolution quasi‐enantiomers 2‐phenylpropionic acid resolution oxazolidin‐2‐ones |
|
|
