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The use of new world primates for biomedical research: an overview of the last four decades
Authors:Laila Brito Torres  Bruno Henrique Silva Araujo  Paulo Henrique Gomes de Castro  Francisco Romero Cabral  Klena Sarges Marruaz  Michelle Silva Araujo  Sergio Gomes da Silva  José Augusto Pereira Carneiro Muniz  Esper Abrão Cavalheiro
Affiliation:1. Departamento de Neurologia e Neurocirurgia, Universidade Federal de S?o Paulo (UNIFESP), S?o Paulo (SP), Brazil;2. Instituto Evandro Chagas (IEC)—Centro Nacional de Primatas (CENP), Ananindeua (PA), Brazil;3. Instituto do Cérebro—Hospital, Israelita Albert Einstein, S?o Paulo (SP), Brazil;4. Universidade de Brasília—UNB, Brasília (DF), Brazil
Abstract:Animal experimentation contributes significantly to the progression of science. Nonhuman primates play a particularly important role in biomedical research not only because of their anatomical, physiological, biochemical, and behavioral similarities with humans but also because of their close phylogenetic affinities. In order to investigate the use of New World primates (NWP) in biomedical research over the last four decades (1966–2005), we performed a quantitative study of the literature listed in bibliographic databases from the Health Sciences. The survey was performed for each genus of NWP that has been bred in the National Center of Primates in Brazil. The number of articles published was determined for each genus and sorted according to the country from which the studies originated and the general scientific field. The data obtained suggests that Brazil is a leader in generating knowledge with NWP models for translational medicine. Am. J. Primatol. 72:1055–1061, 2010. © 2010 Wiley‐Liss, Inc.
Keywords:primates  New World primates  experimental models  biomedical research  translational medicine
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