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Caffeine,selected metabolic gene variants,and risk for neural tube defects |
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| Authors: | Rebecca J Schmidt Paul A Romitti Trudy L Burns Jeffrey C Murray Marilyn L Browne Charlotte M Druschel Richard S Olney |
| Institution: | 1. Department of Public Health Sciences, University of California, Davis, California;2. Department of Epidemiology, University of Iowa, Iowa City, Iowa;3. Departments of Pediatrics and Biology, University of Iowa, Iowa City, Iowa;4. Congenital Malformations Registry, New York State Department of Health, Troy, New York;5. National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia |
| Abstract: | |
| Keywords: | caffeine gene‐environment interaction effect modification cytochrome P450 CYP1A2 N‐acetyltransferase NAT2 embryo mammalian metabolism maternal exposure adverse effects neural tube defects spinal dysraphism encephalocele |