Identification of channel-forming activity in the cell wall of Corynebacterium glutamicum. |
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Authors: | M Niederweis E Maier T Lichtinger R Benz and R Krmer |
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Institution: | M Niederweis, E Maier, T Lichtinger, R Benz, and R Krämer |
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Abstract: | The cell wall of the gram-positive Corynebacterium glutamicum was prepared. It contained an ion-permeable channel with a single-channel conductance of about 6 nS in 1 M KCl. The mobility sequence of the ions in the channel is similar to that in the aqueous phase, suggesting that it is a water-filled channel wide enough to allow unhindered diffusion of ions. The results indicate that we have identified the hydrophilic pathway through the mycolic acid layer of C. glutamicum. |
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