蛋白亚硝基化研究进展及其在植物抗病中的作用

蛋白亚硝基化（S-nitrosylation）是一种在一氧化氮作用下与蛋白半胱氨酸巯基共价结合，使巯基-SH转化为-SNO的反应。作为一种氧化还原依赖的翻译后调控形式，蛋白亚硝基化对多种蛋白的功能具有调节作用，越来越多的证据表明蛋白亚硝基化在植物抗病中发挥重要的作用。简要介绍了蛋白巯基亚硝基化的特点、检测方法、功能研究以及在植物抗病调节方面的最新进展。

Progress in Research Techniques of Protein S-nitrosylation and Its Role in Plant Disease Resistance

S-nitrosylation,the covalent attachment of an Nitric oxide(NO) moiety to Cys residues of proteins,resulting in the formation of S-nitrosothiols(SNO),is a prevalent posttranslational protein modification involved in redox-based cellular signaling.S-nitrosylation has been shown to regulate the function of many proteins which are involved in a wide array of cellular activities.The growing body of evidence now suggested that S-nitrosylation may also have a centrol function in plant disease resistance.The basic ...