Fast prediction of RNA-RNA interaction |
| |
Authors: | Raheleh Salari Rolf Backofen and S Cenk Sahinalp |
| |
Institution: | (1) School of Computing Science, Simon Fraser University, Burnaby, Canada;(2) Institute f?r Informatik, Albert-Ludwigs-Universit?t, Freiburg, Germany |
| |
Abstract: | Background Regulatory antisense RNAs are a class of ncRNAs that regulate gene expression by prohibiting the translation of an mRNA by
establishing stable interactions with a target sequence. There is great demand for efficient computational methods to predict
the specific interaction between an ncRNA and its target mRNA(s). There are a number of algorithms in the literature which
can predict a variety of such interactions - unfortunately at a very high computational cost. Although some existing target
prediction approaches are much faster, they are specialized for interactions with a single binding site. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|