Hepatic uptake of heme and hemopexin but not albumin |
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Authors: | Ham Heng Liem |
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Institution: | Department of Biochemistry, Scripps Clinic and Research Foundation, La Jolla, Calif. 92037, U.S.A. |
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Abstract: | 3H] Heme and 125I-labeled hemopexin are taken up by the rabbit liver maximally 1 h after injection; 131I-labeled albumin however is not taken up, even when heme circulates in excess of the heme-binding capacity of hemopexin. Thus, hepatic engulfment of heme in vivo appears to be facilitated by hemopexin but not by albumin. |
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