Long-term memory in Alzheimer's disease. |
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Authors: | D A Fleischman J Gabrieli |
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Affiliation: | Department of Neurological Sciences, Section of Cognitive Neuroscience, Rush Medical College, Rush Alzheimer's Disease Center, Rush-Presbyterian-Saint Luke's Medical Center, 1645 West Jackson, Suite 450, Chicago, Illinois 60612, USA. dfleisch@rush.edu |
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Abstract: | Recent findings have further characterized the neural and psychological bases of long-term memory failure in Alzheimer's disease. Convergent volumetric neuroimaging studies indicate that loss of episodic memory is specifically related to early-stage limbic-diencephalic pathology, and that non-mnemonic impairment is specifically related to later-stage temporal-neocortical pathology. Recent studies of Alzheimer's disease have also reported informative cognitive dissociations in semantic memory and implicit memory. |
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