| 侧脑室注射牛胰多肽对家兔糖耐量和血清胰岛素浓度的影响 |
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| 引用本文： | 曲瑞瑶,顾增发. 侧脑室注射牛胰多肽对家兔糖耐量和血清胰岛素浓度的影响[J]. 生理学报, 1984, 0(4) |
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| 作者姓名： | 曲瑞瑶 顾增发 |
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| 作者单位： | 北京第二医学院生理教研组，北京医学院基础医学研究所消化、生殖生理研究室 进修教师 |
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| 摘 要： | 在家兔侧脑室内微量注射牛胰多肽能增加其糖耐量及血清胰岛素浓度。这种作用与牛胰多肽注射剂量有明显依从关系,并被预先皮下注射阿托品所部分阻断。结果提示,中枢给予牛胰多肽可能部分通过迷走神经途径增加血清胰岛素的释放而增加糖耐量。
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| 关 键 词： | 牛胰多肽 侧脑室 糖耐量 血清胰岛素 阿托品 |
EFFECT OF INTRACEREBRO-VENTRICULAR INJECTION OF BOVINE PANCREATIC POLYPEPTIDE(BPP)ON GLUCOSE TOLERANCE AND SERUM INSULIN CONCENTRATION IN RABBITS |
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| QU RUI-YAO,GU ZENG-FA. EFFECT OF INTRACEREBRO-VENTRICULAR INJECTION OF BOVINE PANCREATIC POLYPEPTIDE(BPP)ON GLUCOSE TOLERANCE AND SERUM INSULIN CONCENTRATION IN RABBITS[J]. Acta Physiologica Sinica, 1984, 0(4) |
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| Authors: | QU RUI-YAO GU ZENG-FA |
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| Abstract: | Glucose tolerance and serum insulin concentration of rabbits were increasedby injecting BPP into the lateral ventricles and showed a marked dose-dependentrelationship.The effects of BPP were partly abolished by injection of atropine.This is probably due to release of insulin brought about through the action of vagusnerves. |
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| Keywords: | bovine pancreatic polypeptide(BPP) cerebro-ventricular glucose tolerance serum insulin atropine |
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