Conservation of avian Z chromosomes as revealed by comparative mapping of the Z-linked aldolase B gene |
| |
Authors: | Nanda I Schmid M |
| |
Institution: | Department of Human Genetics, University of Würzburg, Würzburg, Germany. |
| |
Abstract: | A chicken Z-linked BAC probe containing the aldolase B gene was used for fluorescence in-situ hybridization (FISH) mapping in four different avian species. The biotinylated BAC clone showed distinct unique hybridization sites on the structurally different Z chromosomes. This result, together with previous data, lends credence to the notion that, despite undergoing structural rearrangements, the gene content of the avian Z chromosome remained conserved during evolution. Our study also demonstrates the feasibility of using large genomic clones for comparative mapping of Z-linked genes in birds. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|