FragmentationAnalyzer: An open‐source tool to analyze MS/MS fragmentation data |
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| Authors: | Harald Barsnes Ingvar Eidhammer Lennart Martens |
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| Affiliation: | 1. Department of Informatics, University of Bergen, Bergen, Norway;2. Department of Medical Protein Research, Ghent, Belgium;3. Department of Biochemistry, Ghent University, Ghent, Belgium |
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| Abstract: | A thorough understanding of the fragmentation processes in MS/MS can be a powerful tool in assessing the resulting peptide and protein identifications. We here present the freely available, open‐source FragmentationAnalyzer tool ( http://fragmentation‐analyzer.googlecode.com ) that makes it straightforward to analyze large MS/MS data sets for specific types of identified peptides, using a common set of peptide properties. This enables the detection of fragmentation pattern nuances related to specific instruments or due to the presence of post‐translational modifications. |
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| Keywords: | Bioinformatics MS fragmentation MS/MS Post‐translational modification |
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