Three dimensional (3D) analysis of the morphological changes induced by 50 Hz magnetic field exposure on human lymphoblastoid cells (Raji) |
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| Authors: | Lisi A Pozzi D Pasquali E Rieti S Girasole M Cricenti A Generosi R Serafino A L Congiu-Castellano A Ravagnan G Giuliani L Grimaldi S |
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| Institution: | Istituto di Medicina Sperimentale - CNR, Via Fosso del Cavaliere, Roma, Italy. |
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| Abstract: | Human Raji B lymphoid cells after exposure for 64 h to a 1 mT (rms) 50 Hz sinusoidal magnetic field showed a reorganization of membrane and cytoskeletal components. Atomic force microscopy in air revealed several modifications in 80% of the exposed cells, such as loss of microvilli-like structures followed by progressive appearance of membrane introflections. This change in plasma membrane morphology was also accompanied by a different actin distribution, as detected by phalloidin fluorescence. These observations support our previous hypothesis that electric and magnetic fields may modify the plasma membrane structure. |
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