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R/Bioconductor在Affymetrix表达芯片中的应用
引用本文:甄一松,张伟丽,吴青,肖成路. R/Bioconductor在Affymetrix表达芯片中的应用[J]. 生物信息学, 2011, 9(2): 138-141,145. DOI: 10.3969/j.issn.1672-5565.2011.02.010
作者姓名:甄一松  张伟丽  吴青  肖成路
作者单位:1. 中国医学科学院北京协和医学院,阜外心血管病医院,中德分子医学研究室,北京100037
2. 北京大学分子医学研究所心血管发育实验室,北京,100871
基金项目:中国医学科学院、北京协和医学院CMB基金和国家自然科学基金支持(31000644)支持
摘    要:R是用于统计计算和数据作图的编程语言和程序设计环境,能在多种平台下编译和运行。Bioconductor也是免费开源的程序设计环境,它主要基于统计编程语言R,用于基因组数据的分析。我们通过已发表的数据,包含斑马鱼心肌再生的生物芯片数据,分析源码实例,较为详细地介绍和讲解了R/BioConductor的用法,为推广优秀的免费统计软件提供了一个简单的中文使用手册。

关 键 词:R  BioConductor  生物芯片  心血管医学

Application of R/BioConductor software in microarray analysis
ZHEN Yi-song,ZHANG Wei-li,WU Qing,XIAO Cheng-lu. Application of R/BioConductor software in microarray analysis[J]. Chinese Journal of Bioinformatics, 2011, 9(2): 138-141,145. DOI: 10.3969/j.issn.1672-5565.2011.02.010
Authors:ZHEN Yi-song  ZHANG Wei-li  WU Qing  XIAO Cheng-lu
Affiliation:ZHEN Yi-song1,ZHANG Wei-li1,WU Qing2,XIAO Cheng-lu2(1.Sino-German Laboratory for Molecular Medicine Cardiovascular Institute & Fuwai Hospital,Chinese Academy of Medical Sciences & Peking Union Medical college 167 Beilishilu,Beijing 100037 China,2.Laboratory of Cardiovascular Development,Institute of Molecular Medicine Peking University New Life Science Research Building Beijing 100871,China)
Abstract:R is a free software environment for statistical computing and graphics.It compiles and runs on a wide variety of UNIX platforms,Windows and MacOS.Bioconductor is based primarily on the R programming language and provides tools for the analysis and comprehension of genomic data.The data used in this paper consist of microarray from zebrafish heart regeneration,which has been published in high quality journals.We briefly described the typical data processing step for this sample dataset with implementation o...
Keywords:R  BioConductor
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