Chemotherapy sorting can be used to identify cancer stem cell populations |
| |
| Authors: | Liping Li Bingkun Li Jialiang Shao Xiang Wang |
| |
| Affiliation: | Department of Urology, Huashan Hospital of Fudan University, 12 Wulumuqi Middle Road, Shanghai, 200040, China. |
| |
| Abstract: | Cancer stem cells (CSCs) of bladder transitional cell cancers (BTCC) had not been identified by the reported common methods. According to the phenomenon that CSCs were resistant to chemotherapy, BTCC cell lines T24 and 5637 were cultured with mitomycin C respectively. Cell inhibition assay revealed an increased population of drug resistant cancer cells with a concentration gradient of mitomycin C. The maximal and minimal cell inhibition rate in cell line T24 was 92.5?%?±?1.0 versus 64.1?%?±?1.4 (P?
|
| |
| Keywords: | |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
