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Discovery of new vascular disrupting agents based on evolutionarily conserved drug action,pesticide resistance mutations,and humanized yeast |
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| Authors: | Riddhiman K Garge Hye Ji Cha Chanjae Lee Jimmy D Gollihar Aashiq H Kachroo John B Wallingford Edward M Marcotte |
| Affiliation: | 1. Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA;2. Division of Hematology/Oncology, Boston Children''s Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Stem Cell Institute, Harvard Medical School, Boston, MA 02115, USA;3. US Army Research Laboratory—South, Austin, TX 78758, USA;4. The Department of Biology, Centre for Applied Synthetic Biology, Concordia University, Montreal, QC H4B 1R6, Canada |
| Abstract: | |
| Keywords: | systems biology evolution humanized yeast angiogenesis vascular disrupting agents phenologs epidemiology |